Directions From the Miami Airport or the Fort Lauderdale Airport
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Take the Florida Turnpike South
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Watch for signs where the turnpike splits off to the right and stay on the turnpike (Sign will say FL Turnpike Homestead & Florida City right lane and I-95 and Stadium left lane)
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Stay on the turnpike until it ends in Homestead and Florida City
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You will be exited off on to US Hwy 1 in Florida City
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Stay on US 1 (known as Overseas Hwy - the only road into and out of the Florida Keys)
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Everything in the Keys is referenced by the mile markers on US 1
Mile markers are white numbers in small green boxes on the side of the road
Florida City is MM 120 and Key West is MM zero -
Key Largo Inn is located at MM 99.2 of US 1(Oceanside or left side as you're coming from Miami)
Directions From Key West